Combined iron chelation EXJADE -Ferriprox

[bernstein]

Hi folks,

after many clinical trials the benefit of combined iron chelation is known. Does anyone heared about a combined treatment of Ferriprox and Exjade?

Is there any upcoming trial somewhere?

Please let me know. Thank you

Bernstein

[Neel_R]

Exjade should not be combined with any other chelator as stated by Novartis.

[Narendra]

There have been report of combined intake of chelators by some patients in the US (Children's Hospital Oakland - has started a study on a controlled group) and Greece. Although, they have been using Exjade (Also called Asunra or Desirox) AND Desferal.

[bernstein]

Yes, I know about clinical trials with Deferoxamin (Desferal) and Desirox (Exjade), and also about the initial well tolerate trials with Ferriprox (Deferiprone or Kelfa) and Desferal.

At least I have read about an alternating use of Ferriprox and Exjade in two individuals. But is there also known or planed an clinical trial a combination between the both oral chelators?